
ProtParam
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ProtParam
User-provided sequence:
        10         20         30         40         50         60 
RHMDAMKRGL CCVLLLCGAV FVSPGPGPGM RVLYLLFSFL FIFLMPLPGV FGGIGDPVTC 

        70         80         90        100        110        120 
LKSGAICHPV FCPRRYKQIG TCGLPGTKCC KKPGPGPGAK FVAAWTLKAA AGPGPGKKLS 

       130        140        150        160        170        180 
LTPLVPMPKK QRAQRNRCID TQGEKKTEQK DFDGRSEFAY KKRHPEPRPK KCVRFSQGKP 

       190        200        210        220        230        240 
EAAAKKGNPG TGKKTAGLPV KKAVSEGKPT EKHIQIRSTN GPGPGITFRL RLPCRTILRV 

       250        260        270        280        290        300 
GPGPGDFYIA YRAVVRAKVE AAYHRIDTAG PRAAYTMITF RLRLAAYTRD REGATMAAYE 

       310        320        330        340        350        360 
RSGEVNAKAA YRAKARLRWR AAYTADTVRI DVAAYDELGL NIVMAAYRAC IREFELAAYH 

       370        380        390        400        410        420 
SAIVEFRCAA YRQADWDTGH AAYQDPQSTA AATVLKRAVE LDSESRYPQA LVCYQEGIDL 

       430        440        450        460 
LLQVLKGTKD NTKRCNLREK ISKYMDRAEN IKKYLDQEKE DG 


References and documentation are available.

Number of amino acids: 462

Molecular weight: 50972.30

Theoretical pI: 9.79

Amino acid composition: 
Ala (A)  56	 12.1%
Arg (R)  40	  8.7%
Asn (N)   8	  1.7%
Asp (D)  20	  4.3%
Cys (C)  16	  3.5%
Gln (Q)  14	  3.0%
Glu (E)  22	  4.8%
Gly (G)  41	  8.9%
His (H)   7	  1.5%
Ile (I)  19	  4.1%
Leu (L)  35	  7.6%
Lys (K)  40	  8.7%
Met (M)   9	  1.9%
Phe (F)  16	  3.5%
Pro (P)  32	  6.9%
Ser (S)  14	  3.0%
Thr (T)  25	  5.4%
Trp (W)   3	  0.6%
Tyr (Y)  20	  4.3%
Val (V)  25	  5.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 80

Atomic composition:

Carbon      C	      2265
Hydrogen    H	      3631
Nitrogen    N	       661
Oxygen      O	       628
Sulfur      S	        25

Formula: C2265H3631N661O628S25
Total number of atoms: 7210

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    47300
Abs 0.1% (=1 g/l)   0.928, assuming all pairs of Cys residues form cystines


Ext. coefficient    46300
Abs 0.1% (=1 g/l)   0.908, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is R (Arg).

The estimated half-life is: 1 hours (mammalian reticulocytes, in vitro).
                            2 min (yeast, in vivo).
                            2 min (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.45
This classifies the protein as stable.



Aliphatic index: 73.40

Grand average of hydropathicity (GRAVY): -0.392

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